THE RAM LAB
  • Home
  • Research Team
  • Publications
  • Lab News
  • Cytokines 2025 in Seattle
  • Alumni
  • Lab Photos
  • Join us

Nandan published in Science!

12/24/2024

 
Dr. Nandan Gokhale’s work from our lab highlights the importance of cellular RNA in enhancing MAVS signalosome function, which is crucial for antiviral signaling initiated by RLRs. They reveal that MAVS interacts with RNA through a disordered domain, enhancing its ability to activate transcription of IFNs. They uncover a new layer of regulation to MAVS signaling.

This manuscript is published in Science:
https://www.science.org/stoken/author-tokens/ST-2323/full ​
 
Additionally, Drs. Sonja Best and Adam Hage wrote a beautiful perspective on this work: https://buff.ly/4fxVMcx 
 
UW Medicine news article on this manuscript can be found at 
https://newsroom.uw.edu/news-releases/study-shows-role-of-cells-own-rna-in-antiviral-defense

​

Comments are closed.
Powered by Create your own unique website with customizable templates.
  • Home
  • Research Team
  • Publications
  • Lab News
  • Cytokines 2025 in Seattle
  • Alumni
  • Lab Photos
  • Join us